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The Top Gut Health Supplements of 2023 for a Healthy Digestive System

De Top Darmgezondheid Supplementen van 2023 voor een Gezond Spijsverteringsstelsel

Did you know that the secret to a healthy body and mind may lie in your intestines? Gut health is a crucial aspect of your overall well-being, affecting everything from digestion to mood. With countless gut health supplements on the market, it's essential to know which ones are best for you. In this blog post, we explore the best supplements for gut health of 2023 and dive into probiotics, prebiotics, digestive enzymes, and other natural ingredients. We also share tips for choosing the right supplement for your unique needs. Let's start!

Key points to consider

  • Gut health is essential to overall well-being and can be improved with supplements such as probiotics, prebiotics and digestive enzymes.
  • Check out our list of the best gut health supplements of 2023, chosen based on quality and effectiveness.
  • Maximize benefits by following dosage/timing guidelines, combining as necessary, and making lifestyle changes.

Understanding gut health and its importance

Our gut plays an important role in maintaining our overall health. It is responsible for breaking down food, absorbing nutrients and harboring trillions of microorganisms, including beneficial bacteria, fungi and viruses that make up the gut microbiome. When in balance, the gut microbiome supports digestion, immune function, mood and overall well-being.

However, several factors can disrupt this delicate balance. Some common factors include:

  • Bad diet
  • Stress
  • Medicines
  • Lifestyle choices

These factors can affect gut health, leading to an overgrowth of harmful bacteria, weakened immune function and digestive problems such as bloating, gas and constipation.

This is where gut health supplements come into play. They provide the body with:

  • Probiotics
  • Prebiotics
  • Digestive enzymes
  • Other natural ingredients

These help restore and maintain a healthy gut microbiome.

The Gut Microbiome

The gut microbiome is an intricate ecosystem of trillions of microorganisms that work together to aid in digestion, immune function and other essential processes. Probiotics, which are live bacteria that are beneficial to the digestive system, play an important role in maintaining intestinal health. They help with:

  • Nutrient absorption
  • Regulating the immune system
  • Reducing inflammation
  • Influencing mood and brain function

Natural sources of probiotics include fermented foods such as:

  • Yogurt
  • Kefir
  • Sauerkraut
  • Kimchi

However, many people take probiotic supplements to ensure they get enough of these beneficial bacteria in their daily diets.

Regular consumption of probiotics and prebiotics can eventually help create a balanced gut microbiome, which supports overall gut health.

Factors that influence intestinal health

Several factors can influence the health of your gut microbiome. Diet plays an important role, as consuming too many sugary, processed foods or not enough fiber and whole grains can disrupt the balance of good and bad bacteria.

Addressing these factors through lifestyle changes is a step toward improving gut health. Eating a balanced diet high in fiber, whole grains and probiotics can have beneficial effects on intestinal flora. This in turn helps maintain overall intestinal health. In addition, stress management techniques such as yoga and meditation can benefit both the gut and overall well-being.

Types of Supplements for Gut Health

There are several types of gut health supplements that can support a healthy digestive system. Probiotic supplements provide beneficial bacteria that aid in digestion and immune function, while prebiotic supplements provide fiber that feeds good gut bacteria, promoting their growth.

Digestive enzyme supplements help break down food and improve digestion, and other nutritional supplements, such as L-glutamine, curcumin and zinc, can also support gut health. Incorporating digestive health supplements into your daily routine can further improve overall well-being.

Below we discuss each type of supplement in more detail.

Probiotic Supplements (Probiotics)

Probiotic supplements contain live beneficial bacteria, including several probiotic strains, that support digestion, immunity and overall gut health. They come in different dosages, targeting specific gut health concerns.

Selecting a probiotic supplement requires paying attention to products that contain multiple strains of beneficial bacteria, as each strain provides unique health benefits. Additionally, make sure the supplement contains enough Colony Forming Units (CFUs) to be effective, usually ranging from 1 to 10 billion CFUs per day.

Prebiotic Supplements (Prebiotics)

Prebiotic supplements provide non-digestible fiber that serves as food for the good bacteria in the gut, promoting their growth and overall gut health. These supplements often contain ingredients such as inulin, chicory root or other prebiotic fibers that promote the growth of beneficial intestinal bacteria.

Look for prebiotic supplements with proven prebiotic ingredients, with your individual needs and preferences in mind.

Digestive Enzyme Supplements

Digestive enzyme supplements contain enzymes such as amylase, protease and lipase that help break down carbohydrates, proteins and fats, making it easier for the body to absorb nutrients. These supplements can boost gut health by supporting digestion and reducing intestinal problems such as bloating, gas and indigestion.

A variety of enzymes in a digestive enzyme supplement is essential to ensure there is enough digestive enzymes for different digestive needs.

Other Natural Ingredients

In addition to probiotics, prebiotics and digestive enzymes, some gut health supplements contain other natural ingredients that support gut health and immune health. L-glutamine, an amino acid, can help with the growth and repair of the intestinal lining. Curcumin, a natural compound found in turmeric, has anti-inflammatory properties that can reduce intestinal inflammation related to digestive problems such as IBD and IBS.

Zinc is also essential for maintaining gut health as it helps reduce inflammation, strengthen the intestinal barrier and balance the balance between good and bad bacteria. Including these additional ingredients in your supplement routine can further support gut health.

How to Choose the Right Supplement for Gut Health

Choosing the right supplement for gut health means considering your personal needs, evaluating the quality of the supplement, and tailoring your regimen for optimal gut health support.

Upcoming guidelines will help you assess your needs, determine supplement quality, and adjust your supplement routine for improved effectiveness of your gut health supplements.

Assess Your Needs

To choose the right supplement for gut health, start by determining your specific gut health concerns. These could include problems such as bloating, gas, constipation, or other digestive symptoms.

Once you've identified your concerns, look for supplements that address those issues. For example, if you struggle with poor digestion, consider a probiotic supplement containing specific strains known to improve digestion.

Evaluate the Quality of the Supplement

Evaluating the quality of a product is fundamental when selecting a supplement for gut health. Look for reputable brands with positive customer reviews and a history of producing high-quality supplements.

Additionally, make sure that the supplement contains effective strains of beneficial bacteria and proper dosages. If you're considering taking a probiotic supplement for irritable bowel syndrome (IBS) or IBD, check the product details to see if the probiotics included can help with those specific symptoms.

Personalize Your Supplement Routine

Customizing your supplement routine based on your unique needs and preferences is vital to maximizing the benefits of your supplements for gut health. This may mean adjusting dosages, combining different types of supplements, or seeking professional advice from a healthcare provider.

By personalizing your supplement routine, you'll be better equipped to support your gut health and overall wellness.

Top Recommended Gut Health Supplements of 2023

With so many gut health supplements on the market, it can be challenging to determine which ones are best for your needs. To help you make an informed decision, we've put together a list of the top recommended gut health supplements of 2023, including:

  • The best overall supplement for gut health
  • The best probiotic supplement
  • The best prebiotic supplement
  • The best digestive enzyme supplement

Selected for their quality, effectiveness and customer reviews, these gut health supplements provide you with a solid starting point for your journey to better gut health.

Best Overall Supplement for Gut Health

Our top pick for the best overall supplement for gut health is Culturelle Digestive Daily Probiotic Capsules. This comprehensive supplement addresses multiple aspects of gut health, including digestion, immunity, and balance. With a rating of 4.6 out of 5, it is highly recommended for improving digestive health and bowel function.

Culturelle Digestive Daily Probiotic Capsules contain a special blend of probiotics, prebiotics and enzymes to support digestive health and balance your gut microbiome.

Best Probiotic Supplement

When it comes to probiotics, our top recommendation is Garden of Life Dr. Formulated Probiotics for Women. This high-quality probiotic supplement contains multiple strains of beneficial bacteria, including Lactobacillus acidophilus, known for supporting digestion, immunity and overall gut health.

With positive customer reviews and a focus on addressing women's unique gut health needs, this probiotic supplement is an excellent choice for those looking to improve their gut health through probiotic supplementation.

Best Prebiotic Supplement

For those who need a prebiotic supplement, we recommend Performance Lab Prebiotic. This high-quality prebiotic supplement contains inulin and other prebiotic fibers that help promote the growth of good gut bacteria, supporting overall gut health.

With a focus on delivering a gentle yet effective prebiotic formula, Performance Lab Prebiotic is an excellent choice for those looking to nourish their gut bacteria and improve their gut health.

Best Digestive Enzyme Supplement

Our top pick for the best digestive enzyme supplement is Enzymedica Digest Gold + ATPro. This supplement contains a variety of enzymes that help break down food, reducing intestinal problems such as bloating, gas and indigestion.

With positive customer reviews and a focus on providing a comprehensive digestive enzyme formula, Enzymedica Digest Gold + Plus is a revolutionary product. ATPro is an excellent option for those who want to improve their digestion and intestinal health.

Tips for Maximizing the Benefits of Gut Health Supplements

Following some key guidelines is crucial to maximizing the benefits of your gut health supplements. Ensure correct dosage and timing, combine supplements where necessary and support intestinal health through lifestyle changes.

Next, we'll dive into these tips to help you maximize the benefits of your gut health supplements and promote optimal gut health.

Dosage and Timing

With gut health supplements, proper dosing and timing significantly affects their effectiveness. Always follow the recommended dosages on supplement labels and take your supplements at the right time, usually with meals or at least 30 minutes before.

Consistent use is essential for the best results, so make sure you set up a routine and stick to it.

Combine Supplements

A synergistic effect on intestinal health can be achieved through a combination of supplements such as probiotics and prebiotics. This means that the combined effect of the supplements is more than the sum of their individual effects, resulting in improved gut health and overall well-being.

When combining supplements, always follow the directions on the supplement labels and consult a healthcare provider if you have any questions or concerns.

Supporting Gut Health Through Lifestyle Changes

Supporting your gut health through positive lifestyle changes is just as crucial as taking gut health supplements. Maintaining a healthy diet is key to optimizing your gut health. Here are some ways to improve your gut health.

  • Add nutrient-dense foods like fiber, whole grains and probiotics to your daily meals
  • Avoid processed foods and added sugars
  • Stay hydrated by drinking plenty of water
  • Manage stress levels through relaxation techniques and regular exercise
  • Get enough sleep to support your body's natural healing process

By following these tips, you can promote beneficial intestinal flora and improve your overall gut health.

Manage stress with techniques such as meditation, yoga and deep breathing, which can benefit both the gut and overall well-being. By incorporating these lifestyle changes, you will be better equipped to support your gut health and achieve optimal wellness.


In summary, gut health is a crucial aspect of overall wellness, and gut health supplements can provide essential support for digestion, immunity, and more. By understanding the importance of gut health, exploring the different types of supplements available, and following guidelines for choosing the right supplement and maximizing its benefits, you will be well on your way to a healthy, balanced gut. So take charge of your gut health today and experience the positive effects on your overall well-being!

Frequently Asked Questions

Is it worth taking supplements for gut health?

Gut health supplements can be beneficial for people with IBS and IBD, traveler's diarrhea, and antibiotic side effects.

However, for most people, there are more reliable ways to nourish your gut microbiome.

What are the signs of an unhealthy gut?

Signs of an unhealthy gut include digestive problems such as irritable bowel syndrome, constipation, diarrhea, heartburn or bloating; autoimmune problems such as thyroid problems, rheumatoid arthritis and type 1 diabetes; rashes and allergies; sugar addiction; sleep problems; and unexplained fatigue or lethargy.

What are the benefits of taking supplements for gut health?

Taking supplements for gut health can help boost your immune system, improve digestion, reduce digestive problems, and positively impact your mental state.

How do I choose the right gut health supplement for my needs?

Consider your unique needs and do your research to find the best quality supplement for you, tailored to your personal gut health goals.

What is the difference between probiotics and prebiotics?

Probiotics are beneficial bacteria that aid digestion and immunity, while prebiotics nourish the good gut bacteria, encouraging their growth and overall gut health.

Check if any food or ingredient has gluten

Check any ingredient like white bread to read more about its likely gluten content.

What is Tolerase® G?

What is Tolerase® G?

A New Approach for People with Gluten Sensitivity: Explore the Science and Benefits of Tolerase® G.

Relief from Gluten Sensitivity

In the fight against gluten, there is a unique supplement that stands out: the anti-gluten pills from Little Helpers with 100% Tolerase® G.

This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1 ) ​. Additionally, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten's toxicity ( 2 ) ( ​​3 ) ​.

On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What are Gluten?

Gluten is a group of proteins found primarily in grains such as wheat, barley and rye. These complex proteins give shape, strength and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why approximately 13% of the world's population is sensitive to gluten in the diet (1)​.

The Effect of Tolerase® G

It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).

Studies have shown that a newly identified prolyl endoprotease, derived from Aspergillus niger, can effectively break down gluten proteins. This enzyme works optimally at a pH of 4-5, remains stable at a pH of 2 and is completely resistant to digestion with pepsin ( 2 ). Additionally, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that hardly any gluten reaches the duodenum ( 3 ). This implies that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity. This gives people the opportunity to (occasionally) give up their strict gluten-free diet ( 3 ).

Unique Enzyme Solution

Discover how our pills with 100% Tolerase® G help with the digestion of gluten and support your lifestyle in a clear video.

Little Helpers & Tolerase® G: Stronger Together in the Fight Against Gluten.

At Little Helpers we are proud of our unique collaboration with the manufacturer of Tolerase® G DSM . Together we have spent 2.5 years researching and working tirelessly on the development and perfection of our gluten digestion pill, which contains 100% Tolerase® G.

Our shared commitment to quality and effectiveness has resulted in a product that is unrivaled on the market. We have chosen to produce locally in Europe to ensure the highest quality standards and control.

Our pill has proven to be many times more effective than those of our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That's why we encourage everyone to try it and experience the benefits for themselves!

Superior gluten degradation

Tolerase® G is many times more effective than any other supplement available and is the only enzyme scientifically proven to be effective enough to break down gluten to the point that the body no longer responds to it.