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Do I have a gluten allergy?

Heb ik glutenallergie?

The short answer is: no! But maybe you have gluten intolerance or gluten sensitivity.

Gluten allergy is a commonly used term that is often incorrectly used to indicate gluten intolerance or gluten sensitivity.

An allergy causes an excessive response by the immune system. However, this reaction does not occur with gluten.

However, you may suffer from gluten intolerance or gluten sensitivity. We would be happy to tell you more about this.

What is gluten intolerance (celiac disease)?

Celiac disease, which is pronounced seuliakia, is the official medical name for gluten intolerance. Celiac disease affects approximately 175,000 people in the Netherlands, approximately 1% of the population, but what is it actually?

If you have gluten intolerance, you cannot tolerate gluten. Consuming foods containing gluten leads to damage to the lining of the small intestine. This results in the death of healthy intestinal villi. Gluten intolerance is an autoimmune disease, which means that the immune system attacks itself. Properly functioning cells in the body are attacked by the body producing antibodies, which causes an inflammatory response.

What is gluten sensitivity?

Gluten intolerance and gluten sensitivity are not the same. The autoimmune reaction that occurs with gluten intolerance does not occur with gluten sensitivity.

This ensures that with gluten sensitivity you experience the complaints after eating gluten, but these are not detectable in the blood or intestines. Because the complaints are so broad and it is not actually possible to determine that gluten sensitivity is the cause and not something else, people sometimes live with this their entire lives without knowing about it.

In the Netherlands, it is estimated that as many as 1.75 million people suffer from gluten sensitivity.

What are the symptoms of gluten intolerance and gluten sensitivity?

Gluten intolerance and gluten sensitivity can lead to many different complaints and vary from mild to serious. We have listed the most common symptoms for you:

Intestinal complaints:

  • Stomach ache
  • Diarrhea
  • Constipation
  • Bloated feeling
  • Sticky, smelly loose stools

Other physical complaints:

  • Weight loss, underweight
  • Bone decalcification
  • Fatigue
  • Headache
  • Skin rash
  • Anemia

Mental complaints:

  • Decreased appetite
  • Mood swings

Complaints in children:

  • Delayed puberty
  • Tearfulness
  • Growth disorders

Gluten intolerance test

If you are curious whether the complaints you are experiencing are related to a possible gluten intolerance or gluten sensitivity, you can have this tested in various ways:

Self test

These tests are available via web shops or the dryer. All these tests work in principle the same: a small amount of blood is taken by pricking your finger. The test then checks whether there are TG2 antibodies in your blood (these are the antibodies against gluten). Unfortunately, it sometimes happens that the test gives a negative result even though there is indeed a gluten intolerance. If you have obvious complaints, it may be advisable to request a specialized test from your GP.

Blood tests

A GP can help you by requesting a specialized blood test, which checks with high accuracy whether there are antibodies against gluten in your blood. If these are not present, gluten intolerance is almost certainly excluded.

Visual examination (gastroscopy)

If more extensive examination is necessary, a gastroscopy is performed. This is a visual examination of the intestine, in which a tube is guided via the esophagus and stomach to the first part of the small intestine, the duodenum. A small piece of intestinal tissue is then removed and examined under a microscope for damaged intestinal villi. Gluten intolerance can be definitively diagnosed using gastroscopy.

Gluten free diet

If gluten intolerance has been ruled out and you still suffer from complaints, you can remove gluten from your diet, possibly with the help of a dietitian, to observe whether the symptoms decrease. If the symptoms decrease, you are probably gluten sensitive and it may be smart to continue your gluten-free diet.

Gluten-free food

For people who are gluten intolerant or gluten sensitive, a gluten-free diet is often the only solution that can reduce or prevent complaints. But despite the fact that there are more and more gluten-free alternatives available these days, eating gluten-free is not always easy.

Gluten is found in grains such as wheat, rye and spelt, which is why they are present in many products that contain these grains. These products should all be avoided, but even then, gluten can still unintentionally end up in your food. Research shows that even when people follow a gluten-free diet, they still consume between 200 and 3,000 mg of gluten per day.¹ It can be difficult to keep control of the diet, especially outside the home. On holiday, in a restaurant or at friends' homes, a mistake is easily made and, despite the best intentions, gluten or traces of gluten regularly end up in the food.

Tips for people with a gluten intolerance or gluten sensitivity

  • Every body is unique. Work with a dietitian to ensure your diet is your best self.
  • Tell your friends and family about your complaints and why you really can't eat certain things.
  • Plan ahead and check with restaurants in advance about their gluten-free options and clearly indicate that you have a gluten intolerance when making reservations. This way, the kitchen staff can take your dietary requirements into account.
  • Go for an extra layer of protection with our Anti-Gluten Pills, which help you break down the unwanted gluten you ingest and prevent complaints.
  • A life without gluten doesn't have to be boring! The internet is packed with delicious gluten-free alternatives that you can try. Enjoy!


1) F. van Overbeek et al.. 'The daily gluten intake in relatives of patients with celiac disease compared with that of the general Dutch population', Eur J Gastroenterol Hepatol, 1997, vol. 9, no. 11, p1097-9.

Check if any food or ingredient has gluten

Check any ingredient like white bread to read more about its likely gluten content.

What is Tolerase® G?

What is Tolerase® G?

A New Approach for People with Gluten Sensitivity: Explore the Science and Benefits of Tolerase® G.

Relief from Gluten Sensitivity

In the fight against gluten, there is a unique supplement that stands out: the anti-gluten pills from Little Helpers with 100% Tolerase® G.

This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1 ) ​. Additionally, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten's toxicity ( 2 ) ( ​​3 ) ​.

On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What are Gluten?

Gluten is a group of proteins found primarily in grains such as wheat, barley and rye. These complex proteins give shape, strength and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why approximately 13% of the world's population is sensitive to gluten in the diet (1)​.

The Effect of Tolerase® G

It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).

Studies have shown that a newly identified prolyl endoprotease, derived from Aspergillus niger, can effectively break down gluten proteins. This enzyme works optimally at a pH of 4-5, remains stable at a pH of 2 and is completely resistant to digestion with pepsin ( 2 ). Additionally, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that hardly any gluten reaches the duodenum ( 3 ). This implies that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity. This gives people the opportunity to (occasionally) give up their strict gluten-free diet ( 3 ).

Unique Enzyme Solution

Discover how our pills with 100% Tolerase® G help with the digestion of gluten and support your lifestyle in a clear video.

Little Helpers & Tolerase® G: Stronger Together in the Fight Against Gluten.

At Little Helpers we are proud of our unique collaboration with the manufacturer of Tolerase® G DSM . Together we have spent 2.5 years researching and working tirelessly on the development and perfection of our gluten digestion pill, which contains 100% Tolerase® G.

Our shared commitment to quality and effectiveness has resulted in a product that is unrivaled on the market. We have chosen to produce locally in Europe to ensure the highest quality standards and control.

Our pill has proven to be many times more effective than those of our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That's why we encourage everyone to try it and experience the benefits for themselves!

Superior gluten degradation

Tolerase® G is many times more effective than any other supplement available and is the only enzyme scientifically proven to be effective enough to break down gluten to the point that the body no longer responds to it.